In 2012, Professor Shinya Yamanaka from Japan was awarded the Nobel Prize in Physiology or Medicine for his groundbreaking work. He became the first person to successfully transform fully differentiated somatic cells into embryonic stem cells in a laboratory setting. By "turning back the clock" on mouse skin cells, he reversed their differentiation and restored their ability to become pluripotent stem cells. This achievement had a profound impact on the development of regenerative medicine and advanced therapies.
In 2013, the Japanese government announced a 10-year investment of 110 billion yen to support research in regenerative medicine, with the goal of becoming a global leader in the field. In 2014, they further amended and established new laws on regenerative medicine to accelerate the development of clinical trials. These efforts have positioned Japan as one of the most open and technologically advanced markets for stem cell therapies, making significant progress in the field of global stem cell treatment development.